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Nucleotide addition cycle of bacterial RNA polymerase and NusG-dependent transcription pausing

Programmable RNA targeting by bacterial Argonaute nucleases (Lisitskaya, L. et al. Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity. Nat Commun 13, 4624 (2022).

Alternative pathways for open promoter complex formation (from Structural basis of ribosomal RNA transcription regulation)

CryoEM structure of the rRNA promoter open complex (from Structural basis of ribosomal RNA transcription regulation)

Close-up views of RNA polymerase and DNA interactions in the rRNA promoter open complex (from Structural basis of ribosomal RNA transcription regulation)

CryoEM structures of the rRNA promoter complex with DksA/ppGpp (from Structural basis of ribosomal RNA transcription regulation)

Structure of E. coli RNA polymerase holoenzyme in complex with DksA/ppGpp

Assembly of DksA and ppGpp to RNAP triggers conformational changes in RNAP and DksA

E. coli sigma70 holoenzyme

Rifampin resistant and compensatory mutations in bacterial RNA polymerase

Structural basis of transcription initiation by bacterial RNA polymerase

Archaeal RNA polymerase transcription